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geomx digital spatial profiler (dsp) software  (GraphPad Software Inc)


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    Structured Review

    GraphPad Software Inc geomx digital spatial profiler (dsp) software
    3D model set-up for <t>GeoMx</t> <t>DSP.</t> (A) The 3D tumouroid set-up and (B) sectioning of the 3D tumouroids for GeoMx DSP. Diagrams were created using Smart Servier Medical Art.
    Geomx Digital Spatial Profiler (Dsp) Software, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/geomx digital spatial profiler (dsp) software/product/GraphPad Software Inc
    Average 90 stars, based on 1 article reviews
    geomx digital spatial profiler (dsp) software - by Bioz Stars, 2026-06
    90/100 stars

    Images

    1) Product Images from "Spatial transcriptomic interrogation of the tumour-stroma boundary in a 3D engineered model of ameloblastoma"

    Article Title: Spatial transcriptomic interrogation of the tumour-stroma boundary in a 3D engineered model of ameloblastoma

    Journal: Materials Today Bio

    doi: 10.1016/j.mtbio.2023.100923

    3D model set-up for GeoMx DSP. (A) The 3D tumouroid set-up and (B) sectioning of the 3D tumouroids for GeoMx DSP. Diagrams were created using Smart Servier Medical Art.
    Figure Legend Snippet: 3D model set-up for GeoMx DSP. (A) The 3D tumouroid set-up and (B) sectioning of the 3D tumouroids for GeoMx DSP. Diagrams were created using Smart Servier Medical Art.

    Techniques Used:

    Invasion of AM cells to different stroma. (A) Invasion of AM-1 cells within the 3D tumouorids shown from H&E-stained samples and GeoMx Profiler scanned samples, green = Pan Cytokeratin (PanCK), blue = DNA. scale bars = 250 μm and 1.5mm respectively. White lines = tumour mass and stroma boundary, orange lines = invasion of tumour cells to the surrounding stroma. (B) Invasion distance of AM-1 cells from the tumour mass to acellular, HGF, and hOB stroma at day 14. (C) Correlation heatmap of differentially expressed genes in invasion pathway in AM-1 tumouroids with acellular, HGF, and hOB. Heatmap presents log 2 change from Mean. T-test (non-paired), BH test correction, and tested by Factors. (D) Plot showing significant gene change. The inner ring represents the percentage of pathway genes significantly changed in the presence of each stroma type. The outer ring indicates the relative fold change in the gene expression observed for each gene in the subgroups. Gene counts of (E) MMP3, (F) BMP2, and (G) STAT3 in AM-1 tumouroids with acellular, HGF and hOB stroma. One-Way ANOVA, Dunnet's Post Hoc; p-values 0.05 < *, 0.005 < **, and 0.0005 < ***. Diagrams were created using Smart Servier Medical Art.
    Figure Legend Snippet: Invasion of AM cells to different stroma. (A) Invasion of AM-1 cells within the 3D tumouorids shown from H&E-stained samples and GeoMx Profiler scanned samples, green = Pan Cytokeratin (PanCK), blue = DNA. scale bars = 250 μm and 1.5mm respectively. White lines = tumour mass and stroma boundary, orange lines = invasion of tumour cells to the surrounding stroma. (B) Invasion distance of AM-1 cells from the tumour mass to acellular, HGF, and hOB stroma at day 14. (C) Correlation heatmap of differentially expressed genes in invasion pathway in AM-1 tumouroids with acellular, HGF, and hOB. Heatmap presents log 2 change from Mean. T-test (non-paired), BH test correction, and tested by Factors. (D) Plot showing significant gene change. The inner ring represents the percentage of pathway genes significantly changed in the presence of each stroma type. The outer ring indicates the relative fold change in the gene expression observed for each gene in the subgroups. Gene counts of (E) MMP3, (F) BMP2, and (G) STAT3 in AM-1 tumouroids with acellular, HGF and hOB stroma. One-Way ANOVA, Dunnet's Post Hoc; p-values 0.05 < *, 0.005 < **, and 0.0005 < ***. Diagrams were created using Smart Servier Medical Art.

    Techniques Used: Staining, Gene Expression



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    geomx digital spatial profiler (dsp) software  (GraphPad Software Inc)
    90
    GraphPad Software Inc geomx digital spatial profiler (dsp) software
    3D model set-up for <t>GeoMx</t> <t>DSP.</t> (A) The 3D tumouroid set-up and (B) sectioning of the 3D tumouroids for GeoMx DSP. Diagrams were created using Smart Servier Medical Art.
    Geomx Digital Spatial Profiler (Dsp) Software, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/geomx digital spatial profiler (dsp) software/product/GraphPad Software Inc
    Average 90 stars, based on 1 article reviews
    geomx digital spatial profiler (dsp) software - by Bioz Stars, 2026-06
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    3D model set-up for GeoMx DSP. (A) The 3D tumouroid set-up and (B) sectioning of the 3D tumouroids for GeoMx DSP. Diagrams were created using Smart Servier Medical Art.

    Journal: Materials Today Bio

    Article Title: Spatial transcriptomic interrogation of the tumour-stroma boundary in a 3D engineered model of ameloblastoma

    doi: 10.1016/j.mtbio.2023.100923

    Figure Lengend Snippet: 3D model set-up for GeoMx DSP. (A) The 3D tumouroid set-up and (B) sectioning of the 3D tumouroids for GeoMx DSP. Diagrams were created using Smart Servier Medical Art.

    Article Snippet: Individual genes were plotted using GraphPad Software (La Jolla, CA, USA) and their statistical tests were completed using the GeoMx Digital Spatial Profiler (DSP) Software.

    Techniques:

    Invasion of AM cells to different stroma. (A) Invasion of AM-1 cells within the 3D tumouorids shown from H&E-stained samples and GeoMx Profiler scanned samples, green = Pan Cytokeratin (PanCK), blue = DNA. scale bars = 250 μm and 1.5mm respectively. White lines = tumour mass and stroma boundary, orange lines = invasion of tumour cells to the surrounding stroma. (B) Invasion distance of AM-1 cells from the tumour mass to acellular, HGF, and hOB stroma at day 14. (C) Correlation heatmap of differentially expressed genes in invasion pathway in AM-1 tumouroids with acellular, HGF, and hOB. Heatmap presents log 2 change from Mean. T-test (non-paired), BH test correction, and tested by Factors. (D) Plot showing significant gene change. The inner ring represents the percentage of pathway genes significantly changed in the presence of each stroma type. The outer ring indicates the relative fold change in the gene expression observed for each gene in the subgroups. Gene counts of (E) MMP3, (F) BMP2, and (G) STAT3 in AM-1 tumouroids with acellular, HGF and hOB stroma. One-Way ANOVA, Dunnet's Post Hoc; p-values 0.05 < *, 0.005 < **, and 0.0005 < ***. Diagrams were created using Smart Servier Medical Art.

    Journal: Materials Today Bio

    Article Title: Spatial transcriptomic interrogation of the tumour-stroma boundary in a 3D engineered model of ameloblastoma

    doi: 10.1016/j.mtbio.2023.100923

    Figure Lengend Snippet: Invasion of AM cells to different stroma. (A) Invasion of AM-1 cells within the 3D tumouorids shown from H&E-stained samples and GeoMx Profiler scanned samples, green = Pan Cytokeratin (PanCK), blue = DNA. scale bars = 250 μm and 1.5mm respectively. White lines = tumour mass and stroma boundary, orange lines = invasion of tumour cells to the surrounding stroma. (B) Invasion distance of AM-1 cells from the tumour mass to acellular, HGF, and hOB stroma at day 14. (C) Correlation heatmap of differentially expressed genes in invasion pathway in AM-1 tumouroids with acellular, HGF, and hOB. Heatmap presents log 2 change from Mean. T-test (non-paired), BH test correction, and tested by Factors. (D) Plot showing significant gene change. The inner ring represents the percentage of pathway genes significantly changed in the presence of each stroma type. The outer ring indicates the relative fold change in the gene expression observed for each gene in the subgroups. Gene counts of (E) MMP3, (F) BMP2, and (G) STAT3 in AM-1 tumouroids with acellular, HGF and hOB stroma. One-Way ANOVA, Dunnet's Post Hoc; p-values 0.05 < *, 0.005 < **, and 0.0005 < ***. Diagrams were created using Smart Servier Medical Art.

    Article Snippet: Individual genes were plotted using GraphPad Software (La Jolla, CA, USA) and their statistical tests were completed using the GeoMx Digital Spatial Profiler (DSP) Software.

    Techniques: Staining, Gene Expression